The review deals with analysis and classification of literature data on phamacognostic study (botanical characteristics, geographical distribution, chemical composition and use in medicine) of species of Motherwort genus (Leonums L.). The review unveils opportunities for comprehensive study and development of approaches to the standardization of raw materials of Turkistan motherwort (L. turkestanicus V.I. Krecz. & Kuprian). That will allow to expand the range of sources of herbal remedies raw materials in the framework of realization of the state program for import substitution.